A phase 3 trial of GSK’s linerixibat in a liver disease has hit its primary endpoint, keeping the drugmaker on track to ...

Significant correlation shown between blood levels and symptom relief; TH104 was well tolerated with no unexpected ...

Interim results from the ongoing GLISTEN trial of linerixibat, GSK's targeted inhibitor of the ileal bile acid transporter ...

British drugmaker GSK said on Tuesday its experimental therapy, linerixibat, met its main goal in a late-stage trial to treat ...

Data presented at The Liver Meeting include adverse events as well as an assessment of patients’ relief of pruritus symptom scores when correlated to pharmacokinetics of TH104. Patients with ...

Ipsen presents 3 late-breaking presentations and 8 abstracts across rare cholestatic liver disease portfolio at AASLD 2024PARIS, FRANCE, 18 ...

Journalist Annie Lowrey has a rare disease that causes a near-constant itch that doesn't respond to most treatments. She ...

In Livdelzi participants, AEs were reported in 89% and 86% of participants with and without cirrhosis, respectively, versus 89% and 84% in placebo participants. A secondary analysis of pruritus in ...

Closely monitor patients with compensated cirrhosis, concomitant hepatic disease ... and benefits of restarting OCALIVA treatment. Severe pruritus was reported in 23% of patients in the OCALIVA ...

Her PBC has developed into cirrhosis, and she also has arthritis and thyroid disease. The itching drives her nuts sometimes too, she told me. But she does not dwell on it either. “Gosh ...

Pruritus, or chronic itching, is a common symptom of primary biliary cholangitis (PBC), a chronic autoimmune liver disease. According to the National Institute of Diabetes and Digestive and Kidney ...

Chronic itch when living with PBC is attributed to ... I believe that empathising with people living with liver disease is an important factor in ensuring a good level of care.