Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, ...

High-intensity electrical pulses have been medically used to destroy tumors while sparing healthy tissue. But lower-intensity ...

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...

Here, we discover lysophospholipids as endogenous pannexin activators, using activity-guided fractionation of mouse tissue extracts combined with untargeted metabolomics and electrophysiology. We show ...

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of ...

Get Instant Summarized Text (Gist) Research has identified the protein QRICH1 as a potential target for modulating T-cell ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course.

Taking a patient's immune cells and targeting their cancer with them, which is called CAR T cell therapy, is showing promise ...

This kind of inflammation often comes from aging, long-term stress, or exposure to pollution and other harmful substances in ...

In a study co-led by the University of Maryland School of Medicine (UMSOM), researchers have identified a “master regulator” gene, ZNFX1, that may act as a biomarker to help guide treatment in future ...

1University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland. 2Division of Translational Radiation Sciences, Department of Radiation Oncology, University of ...