Research has identified a specific function for K63-linked ubiquitination in signaling pathways, particularly in tumor necrosis factor (TNF)–induced NF-κB activation 5.

Smad6 inhibits IL-1 receptor and Toll-like receptor signaling; thus, it has an inhibitory function analogous to that of Smad7 in the TNF signaling pathway 9.

Intracellular Signaling Pathways Activated by TNF Receptors TNF signaling through TNFR1 and TNFR2 can elicit a variety of cellular responses depending on many factors including the metabolic state ...

The metabolism of bone tumors is extraordinarily complex and involves many signaling pathways and processes, including the tumor necrosis factor (TNF) signaling pathway, which consists of TNF factors ...

A research team led by Prof. Liu Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Science has ...

The bispecific antibody market is experiencing rapid growth, primarily driven by the increasing prevalence of complex chronic diseases, such as cance ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

A new study published in Brain Research suggests that adding okra to the diet can protect against long-term metabolic problems caused by early-life overfeeding. In a rat model, okra supplementation ...

DelveInsight's Rheumatoid Arthritis Pipeline report depicts a robust space with 75+ active players working to develop 80+ ...

This review explores the potential of punicic acid in pomegranate seed oil as a nutraceutical for cardiovascular health.