The deal sees Mikko Rantanen and Taylor Hall go to Carolina, and Martin Necas, Jack Drury and draft picks go to Colorado.
The Chicago Blackhawks reportedly operated as the middleman in a blockbuster three-team trade in the NHL on Friday night.
Topps says the 11-year-old declined the Pirates' deal and will put the one-of-a-kind card — featuring Skenes' autograph and a patch from a game-worn jersey — up for auction instead.