Influence of dengue virus serotypes on the abundance of Aedes …
The Aedes aegypti mosquito is the primary transmitter of pathogenic viruses such as dengue virus (DENV), affecting 390 million people in tropical and subtropical regions worldwide annually (2, 3). This virus has four serotypes, namely, DENV-1, DENV-2, DENV-3, and DENV-4, which provide lifelong immunity ( 4 ).
Circulating dengue virus serotypes and vertical transmission in Aedes …
Dec 23, 2021 · We report here the results of a prospective descriptive study that was conducted to detect the levels of VT in Aedes mosquito larvae and circulating DENV serotypes in patients and Aedes mosquito larvae from December 2015 to March 2017 in …
Circulating dengue virus serotypes and vertical transmission in Aedes …
Interestingly, all four DENV serotypes were detected in Aedes albopictus larvae, which was the prominent immature vectorial form identified throughout the study period in the area, showing 9.8% VT of DENV. With the exception of DENV-4, the other three DENV serotypes were identified in Aedes aegypti larvae with a VT of 8.1%. Conclusion
Genetic diversity of Dengue virus serotypes circulating among Aedes ...
Nov 10, 2021 · Our study was designed to identify and characterize the DENV serotypes circulating in Aedes mosquito populations collected in selected sites in Nigeria. The mosquitoes were collected and identified morphologically to species …
Dengue virus: Etiology, epidemiology, pathobiology, and …
Jan 1, 2025 · Dengue virus is transmitted to humans through the bite of infected Aedes mosquitoes. These mosquitoes are often found in tropical and subtropical regions. Currently, there is no universally licensed antiviral therapy or vaccine that …
Influence of dengue virus serotypes on the abundance of Aedes …
Jan 23, 2024 · Our findings indicate that the mosquito virome is predominantly composed of insect-specific viruses (ISVs) and that infection with different DENV serotypes (DENV-1 and DENV-2) could lead to alterations in the relative abundance of viral families and species constituting the core virome in Aedes spp.
Generation and characterization of genetically and antigenically ...
Dengue is caused by four genetically distinct viral serotypes, dengue virus (DENV) 1-4. Following transmission by Aedes mosquitoes, DENV can cause a broad spectrum of clinically apparent disease ranging from febrile illness to dengue hemorrhagic fever and dengue shock syndrome.
Comparative analysis of the susceptibility of Aedes aegypti and ...
Nov 2, 2023 · There are four serotypes of DENV (DENV-1, DENV-2, DENV-3, and DENV-4). A heteroserotype DENV secondary infection (different serotype from the primary infection) is the greatest risk factor for severe dengue, which can lead to organ failure and death [2].
The effects of DENV serotype competition and co-infection on …
Jun 9, 2021 · The Aedes aegypti mosquito is responsible for the transmission of several medically important arthropod-borne viruses, including multiple serotypes of dengue virus (DENV-1, -2, -3, and -4). Competition within the mosquito between DENV serotypes can affect viral infection dynamics, modulating the transmission potential of the pathogen.
Multiple dengue virus serotypes resistant transgenic Aedes …
Here, we report the development of transgenic Aedes aegypti based on a bioinformatically designed multiple miRshRNA (microRNA-based shRNA) DNA sequence under the control of a blood-meal induced promoter, Carboxypeptidase A, to induce RNAi for DENV in Aedes aegypti, and demonstrate the expression of a synthetic multiple shRNA polycistronic cluste...