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  1. Home | Multimedia Tools and Applications - Springer

    Multimedia Tools and Applications publishes original research on multimedia development and system support tools as well as case studies of multimedia ...

  2. Volumes and issues | Multimedia Tools and Applications - Springer

    Multimedia Tools and Applications publishes original research on multimedia development and system support tools as well as case studies of multimedia ...

  3. MTAP loss: a possible therapeutic approach for glioblastoma

    Dec 26, 2022 · In this article, we review the loss of the 5′-methylthioadenosine phosphorylase (MTAP) gene as a potential therapeutic approach for treating glioblastoma. MTAP encodes a metabolic …

  4. Mesothelioma: molecular pathology and biomarkers

    Aug 7, 2024 · While BAP1, as mentioned above, can aid in distinguishing mesothelioma from lung carcinoma, aberrant MTAP and/or merlin staining can be seen in other malignancies and is thus not …

  5. Mesothelioma: morphologic and immunohistochemical findings

    Apr 3, 2024 · Mesothelioma in situ is now recognized as either a single layer of bland cuboidal mesothelial cells that have lost BAP1, and sometimes MTAP, on immunohistochemical staining, or a …

  6. Aims and scope | Multimedia Tools and Applications - Springer

    Multimedia Tools and Applications publishes original research articles on multimedia development and system support tools, and case studies of multimedia applications. Experimental and survey articles …

  7. Loss of methylthioadenosine phosphorylase immunoreactivity …

    Apr 1, 2024 · To ascertain MTAP status as an independent prognostic factor, we first employed univariate analysis of several key clinical variables and MTAP status for the impact on PFS and OS.

  8. Reduced symmetric dimethylation stabilizes vimentin and promotes ...

    Jun 29, 2022 · Utilizing our invasive cell‐based model, we identified methylthioadenosine phosphorylase (MTAP) and confirmed its suppressive effects on tumorigenesis and metastasis. Patients with low …

  9. Submission guidelines | Multimedia Tools and Applications

    Editorial procedure Single-blind peer review This journal follows a single-blind reviewing procedure. This journal also publishes special/guest-edited issues. The peer review process for these articles is the …

  10. Pitfalls in the evaluation of CDKN2A copy number status in ... - Springer

    Apr 14, 2025 · Although MTAP staining offers the benefit of labeling normal cells as an internal (positive) control, our work shows that it is not always a dependable surrogate marker for CDKN2A status, …