Art and science: Intersections of art and science ... - EMBO reports
Dec 27, 2018 · Art and science have coexisted, often indistinguishable from each other, across time and space. A wealth of early documented examples comes from the Islamic culture, where art and science joined in intricate star‐shaped architectural geometries, and the use of “Nur” (light) and material science to design utensils and lettering in manuscripts 2.
Cellular senescence, p21, and the path to fibrosis
Sep 30, 2024 · A main driver of fibrotic disease is cellular senescence, a state in which cells lose the ability to divide, alter their function, and secrete various pro-inflammatory and bioreactive molecules collectively called the senescence-associated secretory phenotype (SASP) (Hernandez-Segura et al, 2018).Senescent cells are abundant in fibrotic tissue and their elimination using genetic or ...
Fermentation for future food systems: - EMBO reports
Apr 27, 2021 · The growing human population and global warming pose an impending threat for global food security (Linder, 2019).This has prompted a critical re‐examination of the food supply chain from producers to consumers in order to increase the overall efficiency of food production, storage and transport.
The EMBO Journal
4 days ago · This cover highlights the article Deciphering the molecular logic of WOX5 function in the root stem cell organizer by Ning Zhang, Pamela Bitterli, Thomas Laux and colleagues. The image highlights the expression (green color) of WOX5 in the root stem cell organizer, the quiescent center.
The state of the art of bispecific antibodies for treating human ...
Aug 24, 2021 · The US FDA grouped bsAbs into two main classes based on their mechanism of action, namely cell‐bridging bsAbs and antigen‐crosslinking bsAbs (non‐cell‐bridging molecules; Labrijn et al, 2019).Most cell‐bridging bsAbs are designed for cancer treatment by linking immune cells to malignant cells.
The EMBO Journal
ABOUT THE JOURNAL Aims and Scope. Launched in 1982, The EMBO Journal publishes high quality research of broad interest and impact across molecular and cell biology with an emphasis on physiological relevance and molecular mechanism.The Journal is one of four journals owned and run by the European Molecular Biology Organization (EMBO) and published through EMBO Press with support from Wiley and ...
Molecular mechanisms and physiological functions of mitophagy
Jan 13, 2021 · The autophagic system targets impaired mitochondria and delivers them to lysosomes for degradation. This catabolic process, called mitophagy, contributes to maintaining mitochondrial quality control (Pickles et al, 2018) and mitochondrial quantity in multiple cell types.In tissues consuming a large amount of ATP such as brain, skeletal muscle, heart, liver, and kidney, mitochondria are highly ...
RNA ‐based medicine: from molecular mechanisms to therapy
Sep 20, 2023 · The notion of RNA as a regulatory molecule in eukaryotic cells took hold in 1993, when Victor Ambros, Gary Ruvkun and colleagues identified lin‐4 as a regulator of Caenorhabditis elegans development (Lee et al, 1993; Wightman et al, 1993).Curiously, lin‐4 did not encode a protein, but expressed a precursor RNA that is processed into a short, double‐stranded RNA.
EMBO Molecular Medicine
*Median number of days from submission. EMBO Molecular Medicine encourages applying due care in interpreting bibliometric measures such as CiteScore, h5-Index and Journal Impact Factor among others. EMBO Press is a foundation signatory of the San Francisco Declaration on Research Assessment pointing to flaws in the Journal Impact Factor, particularly in its application to the assessment of the ...
Molecular Systems Biology
5 days ago · Several approaches have been designed to tackle the size and inherent noise of single-cell genomics data. This Review discusses the metacell concept, provides recommendations on when and how to use them and includes a tutorial and an integrated pipeline for building and analyzing metacells.