Recognition, diagnosis, and early management of suspected sepsis ...
Jun 18, 2024 · Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response to infection.1 In 2016, the National Institute for Health and Care Excellence (NICE) first published guidance on recognising, diagnosing, and managing suspected sepsis. In May 2022, a statement published by the Academy of Medical Royal Colleges2 (and endorsed by NHS England) on use of the updated ...
Effectiveness of public health measures in reducing the ... - The BMJ
Nov 18, 2021 · Objective To review the evidence on the effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality. Design Systematic review and meta-analysis. Data sources Medline, Embase, CINAHL, Biosis, Joanna Briggs, Global Health, and World Health Organization COVID-19 database (preprints). Eligibility criteria for study selection ...
The PRISMA 2020 statement: an updated guideline for reporting ...
Mar 29, 2021 · The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement ...
PRISMA 2020 explanation and elaboration: updated guidance and …
Mar 29, 2021 · The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess the trustworthiness and applicability of the review findings. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement was developed to facilitate transparent and complete reporting of systematic reviews and has been updated (to PRISMA 2020) to reflect ...
Therapeutic advances in rheumatoid arthritis | The BMJ
Jan 17, 2024 · Rheumatoid arthritis (RA) is one of the most common immune mediated inflammatory diseases. People with rheumatoid arthritis present with pain, swelling, and stiffness that typically affects symmetrically distributed small and large joints. Without effective treatment, significant joint damage, disability, and work loss develop, owing to chronic inflammation of the joint lining (synovium). Over ...
Quality improvement into practice | The BMJ
Mar 31, 2020 · Box 1 Definitions of quality improvement. Improvement in patient outcomes, system performance, and professional development that results from a combined, multidisciplinary approach in how change is delivered.3 The delivery of healthcare with improved outcomes and lower cost through continuous redesigning of work processes and systems.4 Using a systematic change method and strategies to improve ...
Dietary sugar consumption and health: umbrella review - The BMJ
Apr 5, 2023 · Objective To evaluate the quality of evidence, potential biases, and validity of all available studies on dietary sugar consumption and health outcomes. Design Umbrella review of existing meta-analyses. Data sources PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, and hand searching of reference lists. Inclusion criteria Systematic reviews and meta-analyses of ...
How unconscious bias can discriminate against patients and
Nov 3, 2020 · Our assumptions, which we may not even be aware of, can lead to erroneous clinical decisions. More research, awareness, training, and diverse teams are needed to tackle this, Kathy Oxtoby finds Older patients are typically sedentary, you assume—without realising it. A patient you relate to well receives that bit more time and attention, although you’re not aware of giving preferential ...
Covid-19: Two rare vaccine side effects detected in large ... - The BMJ
Feb 26, 2024 · The largest vaccine safety study to date has identified two new, but very rare, side effects associated with covid-19 vaccines—transverse myelitis and acute disseminated encephalomyelitis. The Global Vaccine Data Network cohort study included 99 million vaccinated people from 10 sites across eight countries. Researchers compared the observed with expected rate for 13 neurological, blood, and ...
Advances in management of heart failure | The BMJ
Apr 10, 2024 · Survival. Survival following a diagnosis of heart failure is poor and is highly influenced by age. In the UK, survival approaches 80% at five years for people aged 45-64 but is closer to 20% at five years for those aged ≥85.7 Fortunately, survival rates have improved since 2000, particularly among younger patients.7 Although overall survival is an important outcome, it reflects the combined ...